Adiposity and cancer at major anatomical sites: umbrella review of the literature

Date: 
1 Mar 2017
Source: 
The British Medical Journal
Audience: 
Patients and public
Type of resource: 
Research

Primary analysis focused on cohort studies exploring associations for continuous measures of adiposity. The evidence was graded into strong, highly suggestive, suggestive, or weak after applying criteria that included the statistical significance of the random effects summary estimate and of the largest study in a meta-analysis, the number of cancer cases, heterogeneity between studies, 95% prediction intervals, small study effects, excess significance bias, and sensitivity analysis with credibility ceilings.

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